I'd only want a sequel if it was totally unrelated to the events of the first two and explored more of the world in it (and even then, I'm good -- Blade Runner gave us enough of the streets to let us imagine anything happening in them and 2049 gave us enough of the outer wastelands to let us imagine whatever might be going on beyond them and I'm more than content with that). Explore the themes, have it be about a Replicant, sure, but don't ruin the Deckard/K storylines by pushing them too far. There was an ambiguity and sense of mystery somehow maintained through to the very end and in the wrong hands it'd be destroyed very quickly. A sequel to Blade Runner not only being good but being amazing without stepping on the legacy of the first one at all was an impossible magic act that was somehow pulled off, and I don't want to see someone attempt it yet again. There was already a one in a million chance of this film being as good as it was.